Direct Mail is fully compatible with the following operating systems:
- macOS 10.11 El Capitan
- macOS 10.12 Sierra
- macOS 10.13 High Sierra
- macOS 10.14 Mojave
- macOS 10.15 Catalina
- macOS 11.0 Big Sur
Direct Mail is compatible with both Intel-based and Apple silicon-based Macs.